高危膀胱癌膀胱切除术指征和时机-技术前沿-资讯-生物在线

高危膀胱癌膀胱切除术指征和时机

作者:上海联硕生物科技有限公司 2012-09-06T09:39 (访问量:5785)

高危膀胱癌膀胱切除术指征和时机

Indication and timing of cystectomy in high-risk bladder cancer.
Abstract
PURPOSE OF REVIEW: Although the conservative approach including Bacillus Calmette-Guerin (BCG) therapy is considered as the first-line option in high-risk nonmuscle invasive bladder tumors, cystectomy is often required as an alternative treatment in the case of BCG failure. Considering all the parameters, including clinical data, endoscopic aspects and new biological markers, the question of the indication, and moreover timing, of cystectomy has become crucial.

RECENT FINDINGS: In fact, the real positive effect of BCG remains controversial and its actual benefit in terms of survival is not evident. Therefore, early cystectomy for this population with high risk of progression and metastasis diffusion is clearly a radical approach which can lead to a reduction in specific mortality. Recent articles have studied the parameters involved in this issue to determine the exact timing of cystectomy.

SUMMARY: To avoid delay of appropriate treatment, it is crucial to determine the non-BCG responder population. Unfortunately, no consensual marker is currently available. Nevertheless, multifocal tumors, associated carcinoma in situ, prostatic urethral involvement, tumoral size greater than 3 cm and depth of infiltration are useful parameters in clinical practice to propose early cystectomy. In the future, the crucial question of cystectomy timing may be answered by progress in molecular signatures for bladder cancers.

原文链接:http://www.ncbi.nlm.nih.gov/pubmed/22814883

上海联硕生物科技有限公司 商家主页

地 址: 上海市嘉松中路3555号A1栋

联系人:

电 话: 16621087207

传 真: 总机转807分机

Email:lianshuo@vip.126.com

相关咨询

Axygen耗材的特点和常见问题有哪些? (2021-04-27T14:27 浏览数:9360)

血清移液管的特点、正确使用方法和步骤,都有哪些? (2021-04-23T15:08 浏览数:10449)

LANSO移液吸头买一送一 (2021-04-19T13:30 浏览数:9147)

离心管的作用及注意事项,有哪些? (2021-04-13T14:39 浏览数:11636)

细胞培养皿的用途、注意事项有哪些? (2021-04-06T14:37 浏览数:9799)

关于酪蛋白,你可能还不知道的事情酪蛋白的谜团 (2021-04-06T14:30 浏览数:8539)

联硕生物丨巴氏吸管篇 (2021-03-31T16:58 浏览数:9303)

联硕生物丨移液管篇 (2021-03-29T17:16 浏览数:8894)

酪蛋白钠盐是什么?有哪些作用和特性? (2021-03-29T14:17 浏览数:12115)

联硕生物丨保存管 (2021-03-26T17:10 浏览数:9683)

ADVERTISEMENT